DNA bioassay-on-chip using SERS detection for dengue diagnosis.

نویسندگان

  • Hoan T Ngo
  • Hsin-Neng Wang
  • Andrew M Fales
  • Bradly P Nicholson
  • Christopher W Woods
  • Tuan Vo-Dinh
چکیده

A novel DNA bioassay-on-chip using surface-enhanced Raman scattering (SERS) on a bimetallic nanowave chip is presented. In this bioassay, SERS signals were measured after a single reaction on the chip's surface without any washing step, making it simple-to-use and reducing the reagent cost. Using the technique, specific oligonucleotide sequences of the dengue virus 4 were detected.

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عنوان ژورنال:
  • The Analyst

دوره 139 22  شماره 

صفحات  -

تاریخ انتشار 2014